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From healthy joints and a shiny coat to an extra spring in his step, Petandim™ helps dogs fight oxidative stress in a supplement that’s scientifically formulated to repay your best friend for all the slobbery love he gives you.

30 CHEWABLE TABLETS
 
  • Choose one-time order or monthly subscription before adding to cart.
  • $30-Day Money Back Guarantee
Try our products risk-free. You can return your order within 30 days of purchase for any reason.
 
  • No-Hassle Subscriptions
You can skip a month or cancel your subscription online at any time, so you can choose our best pricing with confidence.
 
  • Give Your Best Friend The Health He Deserves
  • Dogs deepen our ability to love and bring us happiness, and some science suggests they can help us live healthier lives. Now we can return the favor. Leveraging the groundbreaking science behind the leading *Protandim® Nrf2 Synergizer®* for humans, Petandim for Dogs is formulated to increase healthspan and give our 4-legged friends more quality time for tummy rubs and tail wagging.
  • Every cell in a dog’s body contains a protein called Nrf2. When activated by Petandim, over 200 genes get to work to support cellular health and create powerful enzymes that protect them from future oxidative stress. Made by pet parents and backed by nutrigenomics,
  • Petandim helps our fur babies stay healthy and play harder.
Benefits
  • A shinier coat
  • Increased playfulness
  • More energy
  • Supports joint health
  • Supports hearing and eyesight
Associations
  •  
Fight Cellular Stress—a First for Dogs!
  • The first canine supplement formulated to combat cellular stress through Nrf2 activation,Petandim for Dogs is the result of our collaboration with world-renowned pet product formulator William Barnett, DVM.
  • Together, we created a product specifically formulated and properly dosed for canine consumption—a delicate balance that uses the same active ingredients as Protandim but also includes omega-3 fatty acids and collagen, making it like no other canine supplement on the market.
Dog Friendly Taste
With the tastes of bacon, chicken and liver, all in a chewable tablet, giving your dog Petandim will be simple. This all-in-one supplement eliminates the need to purchase separate collagen and omega-3 fatty acids supplements.
  • Certification
LifeVantage is a member of National Animal Supplement Council (NASC) and Petandim has been approved to use the NASC seal. NASC’s overriding goal is to promote the health and well-being of nonhuman food chain animals that are given animal health supplements by their owners, and to protect and enhance the integrity of the animal health product industry. NASC advocates and collectively enforces Good Manufacturing Practice Quality Standard in manufacturing, labeling, and marketing animal health supplements. All NASC members are required to undergo a rigorous independent audit of their facilities. Upon completion of this audit, members are then able to display the NASC Seal of Quality to show consumers they are committed to the “highest current standards of quality in the industry today.  

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PROTANDIM FAQs Click Here to Shop

PROTANDIM FAQs

1. WHAT IS Protandim NRF2 SYNERGIZER?

Protandim Nrf2 Synergizer is the only supplement proven in a peer-reviewed, human clinical study to reduce cellular stress in humans by an average of 40 percent in 30 days. Protandim Nrf2 Synergizer is patent protected and is the subject of 22 peer-reviewed clinical studies. Protandim Nrf2 Synergizer works to support the body’s own protective measures by turning on its internal antioxidant defense system, regulated by the protein Nrf2. When activated, Nrf2 triggers cells to produce naturally occurring antioxidant enzymes as well as housekeeping “cleanup” proteins that work together to deliver balanced protection against cellular stress.

2. WHAT ARE THE ACTIVE INGREDIENTS FOUND IN Protandim NRF2 SYNERGIZER?
  • Withania somnifera (Ashwagandha) root extract (sourced from India)
  • Camellia sinensis (Green Tea) leaf extract (sourced from China)
  • Silybum marianum (Milk Thistle) seed extract (sourced from China)
  • Bacopa monnieri (Bacopa) whole plant extract (sourced from India)
  • Curcuma longa (Turmeric) root extract (sourced from India)

3. WHAT ARE THE OTHER INGREDIENTS IN Protandim NRF2 SYNERGIZER AND WHAT PURPOSE DO THEY SERVE?

DiCalcium Phosphate and Calcium Carbonate (listed as “Calcium” in the Supplement Panel), Microcrystalline Cellulose, Croscarmellose Sodium, Silica, Modi ed Cellulose, Stearic Acid, Magnesium Stearate, Maltodextrin, Medium Chain Triglycerides. The “Other Ingredients” in Protandim Nrf2 Synergizer serve as binding and processing aids during the production of the tablet.

4. ARE THE INGREDIENTS USED IN Protandim NRF2 SYNERGIZER “ORGANIC?”
No, they are not certified organic; however, at LifeVantage, we perform pesticide, herbicide, and heavy metal testing on every lot of raw material to assure we have only safe, high-quality products.

5. ARE THE RAW INGREDIENTS TESTED?

Yes, the Quality Control measures implemented by LifeVantage go beyond industry standards. LifeVantage rigorously tests every lot of active raw material for identity, potency, microbial contamination, pesticides, and heavy metals. Unlike most dietary supplement companies, we also physically audit all of our active raw material suppliers. We perform exhaustive testing to verify that all materials meet or exceed quality specifications.

6. CAN I TAKE THESE INGREDIENTS INDIVIDUALLY AND ACHIEVE THE SAME EFFECT?

No, the individual ingredients in Protandim Nrf2 Synergizer aren’t as effective in activating the Nrf2 pathway as LifeVantage’s botanical blend. Previous studies of Protandim Nrf2 Synergizer have shown a very clear and potent synergy whereby the 5-ingredient blend is significantly more effective than any of the individual ingredients in:
  • Inducing Nrf2
  • Triggering the production of internal antioxidant enzymes, and
  • Stimulating the expression of a variety of cell survival genes.

7. HOW IS Protandim NRF2 SYNERGIZER MANUFACTURED?

The raw ingredients are verified, carefully weighed out, blended, and pressed into tablet form following strict Good Manufacturing Practices (GMP) guidelines. Every lot of finished Protandim Nrf2 Synergizer is tested for compliance with approved specifications in addition to receiving a final quality inspection following dietary supplement regulations. Every lot must, again, meet or exceed established finished product specifications before it can be released by LifeVantage Quality Assurance.

8. DOES THE MANUFACTURER OF Protandim NRF2 SYNERGIZER PROCESS ANY ALLERGENS SUCH AS DAIRY, GLUTEN, ETC?

All Protandim Nrf2 Synergizer manufacturers are required to maintain a strict allergen program to protect against any potential cross-contamination of allergens. These facilities are frequently audited to ensure that the processes and protocols are being strictly adhered to in order to ensure the safety of the product.

9. ARE DYES OR FOOD COLORINGS IN Protandim NRF2 SYNERGIZER?
No, there are no dyes or food colorings in Protandim Nrf2 Synergizer. One of the active ingredients in Protandim Nrf2
Synergizer, Curcuma longa (Turmeric), is intensely yellow, adding to the yellow coloring of the tablet.

10. DOES Protandim NRF2 SYNERGIZER CONTAIN ANY ANIMAL BY-PRODUCTS/IS Protandim NRF2 SYNERGIZER ALL NATURAL?

Protandim Nrf2 Synergizer is 100% Vegetarian, free from gluten, wheat, dairy, gelatin, and yeast.

11. I READ THAT Protandim NRF2 SYNERGIZER CONTAINS MILK THISTLE. IS THERE ANY DAIRY IN Protandim NRF2 SYNERGIZER?

No, Silybum marianum (Milk Thistle) is a plant used in traditional Chinese medicine. While “milk” is in the name, this ingredient does not contain any dairy.

12. ARE DIETARY SUPPLEMENTS A REGULATED INDUSTRY?

Yes, the FDA regulates both finished dietary supplement products and dietary ingredients. Dietary supplements are regulated under a different set of regulations than those covering “conventional” foods and drug products. Manufacturers and distributors of dietary supplements and dietary ingredients are prohibited from marketing products that are adulterated or misbranded.

Firms are responsible for evaluating the safety and labeling of their products in order to comply with the Dietary Supplement Health and Education Act (DSHEA) and FDA regulations. The FDA closely monitors the marketplace for illegal products (products that may be unsafe or make misleading claims) in a variety of ways, including inspections of dietary supplement manufacturers and distributors, dietary supplement websites, consumer complaints, and occasional laboratory analyses of products.

13. DOES Protandim NRF2 SYNERGIZER HAVE FDA APPROVAL?

Although dietary supplement manufacturers must register their facilities with FDA, they are not required to get FDA approval before producing or selling dietary supplements. Manufacturers and distributors must ensure all claims and information on the product label and any other labeling are truthful and not misleading.

Under FDA regulations, all domestic and foreign companies that manufacture, package, label, or hold dietary supplements, including those involved with testing, quality control, and dietary supplement distribution in the U.S., must comply with current Good Manufacturing Practices (cGMPs) for dietary supplements.

14. DOES LIFEVANTAGE MEET CURRENT GOOD MANUFACTURING PRACTICES?

Yes, we meet or exceed cGMPs for Dietary Supplements. LifeVantage establishes the safety and purity of all its ingredients through independent laboratory testing, auditing, and third party certifications. We have one of the most comprehensive quality systems in the industry, and many other companies now request the same quality standards that LifeVantage requires of our manufacturers and suppliers.

15. IS Protandim NRF2 SYNERGIZER A “CERTIFIED” PRODUCT?
Yes, Protandim Nrf2 Synergizer is certified by NSF International. Certification by NSF means that an independent organization has reviewed the manufacturing process of a product and determined that the final product complies with specific standards for safety, quality or performance. NSF certification is recognized by regulatory agencies at the local, state, federal and international level, and NSF periodically conducts audits and product testing to verify that the product continues to comply with the standard.

16. IS Protandim NRF2 SYNERGIZER A BANNED SUBSTANCE FOR WHICH CERTIFICATION IS NEEDED, AS IN THE CASE OF PROFESSIONAL ATHLETES?

No, Protandim Nrf2 Synergizer is not a controlled substance, nor does it contain any banned or controlled substances. The BSCG symbol on the Protandim Nrf2 Synergizer label assures consumers that every lot of Protandim Nrf2 Synergizer has been analyzed and certified by the Banned Substances Control Group (BSCG) to be free of all substances banned by the World Anti-Doping Agency.

17. I DRINK SPECIAL JUICES AND EAT FRUITS AND VEGETABLES FOR MY ANTIOXIDANTS. WHY DO I NEED PROTANDIM NRF2 SYNERGIZER?

Many people mistakenly believe their antioxidant needs are fulfilled by eating blueberries, drinking expensive “miracle juices” and applying antioxidant facial creams. What they don’t realize is that their daily antioxidant needs cannot be fulfilled by consuming any amount of blueberries, dark chocolate, or red wine. Effective antioxidant protection absolutely requires adequate production of the body’s own antioxidant enzymes. Protandim Nrf2 Synergizer contains a unique, patented blend of ingredients that have been proven to stimulate the production of antioxidant enzymes and protect against cellular stress.

18. HOW IS Protandim NRF2 SYNERGIZER DIFFERENT FROM ANTIOXIDANT SUPPLEMENTS?

Instead of providing the body with additional dietary antioxidants, Protandim Nrf2 Synergizer supports your body from within by turning on its own antioxidant defense system. By upregulating the production of antioxidant enzymes and other protective proteins, Protandim Nrf2 Synergizer helps to reduce free radical damage and prepare cells for exposure to future stressors.

Additionally, each antioxidant enzyme can react with and deactivate millions of free radicals every second. This makes them one million times more effective than dietary antioxidants, which can only scavenge free radicals on a “one-to-one” basis. This is why Protandim Nrf2 Synergizer is different than any other dietary supplement on the market today.

19. IS IT BEST TO TAKE Protandim NRF2 SYNERGIZER WITH OR WITHOUT FOOD?
Some of the active ingredients in Protandim Nrf2 Synergizer are fat-soluble, so taking Protandim Nrf2 Synergizer with a meal containing some fat allows the ingredients to be absorbed more efficiently (but it’s not absolutely necessary).

20. HOW MUCH CAFFEINE IS IN Protandim NRF2 SYNERGIZER?
Protandim Nrf2 Synergizer contains 1.8 mg of caffeine per tablet. (By comparison, Starbucks coffee may contain up to 150 mg and “caffeine-free” coffee may contain between 4-7 mg.)

21. WHAT IS THE SHELF LIFE FOR Protandim NRF2 SYNERGIZER?
The shelf life for Protandim Nrf2 Synergizer is three years from the date of manufacture.

22. CAN A PERSON DEVELOP DESENSITIZATION TO Protandim NRF2 SYNERGIZER?

No, there is no known mechanism whereby Protandim Nrf2 Synergizer loses effectiveness over time. The formula has not been changed and bioactivity is monitored to maintain consistent potency with regard to the activation of the Nrf2 transcription factor (the mechanism by which Protandim Nrf2 Synergizer works).

23. ARE THERE SITUATIONS WHERE Protandim NRF2 SYNERGIZER IS NOT RECOMMENDED? WILL Protandim NRF2 SYNERGIZER INTERFERE WITH MY OTHER MEDICATIONS?

As with any supplement, particularly if you have a medical condition, are taking medication or other supplements, you should speak with your healthcare provider before taking Protandim Nrf2 Synergizer. If you experience nausea, vomiting, diarrhea or any other difficulties after taking Protandim Nrf2 Synergizer, discontinue use and consult your healthcare provider.

24. SHOULD I CONTINUE TO TAKE MY OTHER VITAMINS AND ANTIOXIDANTS?
Some Western diets are lacking in certain nutritional elements, so multivitamin supplementation may be beneficial for some people.

25. ARE THERE ANY SIDE EFFECTS TO TAKING Protandim NRF2 SYNERGIZER?

We do not expect there to be any side effects for the typical Protandim Nrf2 Synergizer consumer. However, some individuals may have natural allergic responses or sensitivities to one or more of the ingredients, just as some people are allergic to pollen or penicillin. These allergic responses to Protandim Nrf2 Synergizer generally appear as gastrointestinal disturbances (i.e., stomach ache, diarrhea, vomiting) or sometimes as a headache or rash on the hands or feet. The symptoms typically disappear if Protandim Nrf2 Synergizer use is discontinued.

If you are experiencing any adverse reaction, discontinue use of the product and call (855) 519-7499.

26. WHY DO PEOPLE AGE AND HOW CAN Protandim NRF2 SYNERGIZER HELP SLOW THE CELLULAR AGING PROCESS?

Researchers and scientists agree that aging is the result of cellular deterioration caused by free radicals. It is impossible to avoid free radicals because the food you eat and the air you breathe, as well as stress or even vigorous exercise, can stimulate cells to produce destructive free radicals in staggering numbers.

The human body fights free radicals by producing its own antioxidant enzymes, but as we grow older our bodies produce more free radicals and fewer of these antioxidant enzymes to fight the battle of aging. That’s where Protandim Nrf2 Synergizer plays a critical role by boosting the body’s production of antioxidant enzymes at the cellular level with enough neutralizing capacity to reduce the age-related increase in free radical damage.

27. HOW IS Protandim NRF2 SYNERGIZER A NRF2 ACTIVATOR?

Protandim Nrf2 Synergizer’s results stem from its ability to activate the transcription factor known as Nrf2. Nrf2 is a protein messenger contained in every cell of the body that sends information to the cell’s DNA. Protandim Nrf2 Synergizer contains five ingredients that are known as Nrf2 activators.

When Nrf2 is activated, it enters the nucleus and turns on several hundred genes, known collectively as “survival genes.” These genes enable cells to survive in the face of several different kinds of stress, especially oxidative stress, which occurs when free radicals and other oxidants overwhelm the body’s natural antioxidant enzymes. As an Nrf2 activator, Protandim Nrf2 Synergizer helps keep the body safe from free radicals and oxidants by activating these survival genes.
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AXIO - Why We're Different*

AXIO takes a different approach to energy.
Click Here to Order. 
Specially formulated to give energy to your mind, not just your body. Engineered with Nrf2 ingredients, it’s designed to deliver more mental clarity, focus, and concentration without the jitters or caffeine crash. There’s good energy and there’s bad energy. Sugary, caffeinated energy: bad. Nrf2 engineered energy that naturally kicks your brain into gear without the extra sugar, jitters, or crash: good. We created AXIO with a different approach because we understand that when you’re feeling tired or sluggish, it’s your brain that needs a pick-me-up, not your hyperactivity levels. You need less fog and a more clarity, not a cattle prod. AXIO uses a proprietary blend of ingredients to wake your brain up, increase concentration, and deliver the right kind of energy, right when you need it without the added sugar, low-grade caffeine, or extreme sports packaging. Product-
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Our Purpose

Progress is not essential to the human condition, progress is the human condition.
At LifeVantage curiosity has our attention, science has our back and we recognize–and firmly believe–that your growth is the way of our future.

Find a higher calling with LifeVantage and Venture Higher™

CORE VALUES

​       1. We live our lives with Purpose and Intention.

       2. We provide ALL an Equal opportunity of impact.

       3. We look for opportunities to Celebrate life and Recognize others.

       4. We are Resilient; there is a lesson to be learned in every obstacle.

       5. We are Solution seekers: "keep the paddles in the water."

       6. OUR team, OUR company... Own it!

       7. Lead with Kindness.
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CORE VALUES

​       1. We live our lives with Purpose and Intention.

       2. We provide ALL an Equal opportunity of impact.

       3. We look for opportunities to Celebrate life and Recognize others.

       4. We are Resilient; there is a lesson to be learned in every obstacle.

       5. We are Solution seekers: "keep the paddles in the water."

       6. OUR team, OUR company... Own it!

       7. Lead with Kindness.

 
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PEER-REVIEWED PUBLISHED RESEARCH

PEER-REVIEWED PUBLISHED RESEARCH

PubMed.gov – The National Library of Medicine’s Website
PubMed.gov – Search Results “Oxidative Stress”

If you would like to see the studies that have linked oxidative stress to a particular health concern, go to pubmed.gov and type into the search bar oxidative stress and... (examples may be cancer, heart disease, diabetes, etc).

PubMed.gov – Search Results “Protandim”
PubMed.gov – Search Results “NRF2”
Protandim NRF is NSF certified (quality standards) & BSCG (Banned substances – Olympic, NCAA, NFL) approved. Click on the logos below to learn more!

Get the facts! Use Google Scholar and http://www.Pubmed.gov for reliable information!

Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim
K Velmurugan, J Alam, JM McCord… - Free Radical Biology and …, 2009 - Elsevier
Protandim is an antioxidant supplement that consists of five ingredients, namely,
ashwagandha, bacopa extract, green tea extract, silymarin, and curcumin, each with known
therapeutic properties. Protandim was formulated to combine multiple …
  Cited by 81 Related articles All 32 versions
[PDF] plos.org
[PDF] Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model
J Liu, X Gu, D Robbins, G Li, R Shi, JM McCord… - PloS one, 2009 - journals.plos.org
Oxidative stress is an important contributor to cancer development. Consistent with that,
antioxidant enzymes have been demonstrated to suppress tumorigenesis when being
elevated both in vitro and in vivo, making induction of these enzymes a more potent …
  Cited by 50 Related articles All 33 versions
[PDF] plos.org
[PDF] The chemopreventive effects of Protandim: modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis
D Robbins, X Gu, R Shi, J Liu, F Wang, J Ponville… - PLoS …, 2010 - journals.plos.org
Protandim, a well defined dietary combination of 5 well-established medicinal plants, is
known to induce endogenous antioxidant enzymes, such as manganese superoxide
dismutase (MnSOD). Our previous studies have shown through the induction of various …
  Cited by 32 Related articles All 29 versions
[PDF] academia.edu
Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway
B Joddar, RK Reen, MS Firstenberg… - Free Radical Biology …, 2011 - Elsevier
Human saphenous veins (HSVs) are widely used for bypass grafts despite their relatively
low long-term patency. To evaluate the role of reactive oxygen species (ROS) signaling in
intima hyperplasia (IH), an early stage pathology of the vein-graft disease, and to explore the …
  Cited by 28 Related articles All 19 versions
[HTML] nih.gov
The Dietary Supplement Protandim® Decreases Plasma Osteopontin and Improves Markers of Oxidative Stress in Muscular Dystrophy Mdx Mice
MM Qureshi, WC McClure, NL Arevalo… - Journal of dietary …, 2010 - Taylor & Francis
Therapeutic options for Duchenne muscular dystrophy (DMD), the most common and lethal
neuromuscular disorder in children, remain elusive. Oxidative damage is implicated as a
pertinent factor involved in its pathogenesis. Protandim® is an over-the-counter supplement …
  Cited by 34 Related articles All 25 versions
Elucidating the Role of Protandim and 6‐Gingerol in Protection Against Osteoarthritis
J AbusarahH Benabdoune, Q Shi… - Journal of cellular …, 2017 - Wiley Online Library
Protandim and 6‐gingerol, two potent nutraceuticals, have been shown to decrease free
radicals production through enhancing endogenous antioxidant enzymes. In this study, we
evaluated the effects of these products on the expression of different factors involved in …
  Cited by 20 Related articles All 7 versions
[PDF] physiology.org
Protandim does not influence alveolar epithelial permeability or intrapulmonary oxidative stress in human subjects with alcohol use disorders
EL Burnham, JM McCord, S Bose… - American Journal of …, 2012 - physiology.org
Alcohol use disorders (AUDs), including alcohol abuse and dependence, have been linked
to the development of acute lung injury (ALI). Prior clinical investigations suggested an
association between AUDs and abnormal alveolar epithelial permeability mediated through …
  Cited by 21 Related articles All 7 versions
[HTML] mdpi.com
Protandim protects oligodendrocytes against an oxidative insult
JL Lim, V der Pol, MA Susanne, W Baron, JM McCord… - Antioxidants, 2016 - mdpi.com
Oligodendrocyte damage and loss are key features of multiple sclerosis (MS) pathology.
Oligodendrocytes appear to be particularly vulnerable to reactive oxygen species (ROS) and
cytokines, such as tumor necrosis factor-α (TNF), which induce cell death and prevent the …
  Cited by 6 Related articles All 12 versions
[HTML] physiology.org
Differential effects of vitamin C or Protandim on skeletal muscle adaptation to exercise
DR Bruns, SE Ehrlicher, S Khademi… - Journal of Applied …, 2018 - physiology.org
Maintaining proteostasis is a key mechanism for preserving cell function. Exercise-
stimulated proteostasis is regulated, in part, by redox-sensitive signaling. Several studies
suggest that supplementation with exogenous antioxidants blunts exercise-induced cellular …
  Cited by 9 Related articles All 6 versions
[HTML] nih.gov
[HTML] The effect of Protandim® supplementation on athletic performance and oxidative blood markers in runners
SL Ueberschlag, JR Seay, AH Roberts, PC DeSpirito… - PloS one, 2016 - ncbi.nlm.nih.gov
The purpose of this study determined if oral supplementation of Protandim®(a nutraceutical)
for 90 days improved 5-km running performance and reduced serum thiobarbituric acid-
reacting substances (TBARS) at rest, an indicator of oxidative stress. Secondary objectives …
  Cited by 5 Related articles All 11 versions

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